Reversal of Small, Dense LDL Subclass Phenotype by Weight Loss Is Associated With Impaired Fat Oxidation
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چکیده
منابع مشابه
Ratio of Dense to Buoyant LDL Subclass is Associated with LDL Density Phenotype (VLDL-5)
Background: Dense LDL phenotypes are associated with increased atherogenicity, and are commonly evaluated for the purposes of atherosclerosis research and cardiovascular risk discrimination. Objective: To examine the ability of LDL subclasses, expressed as a ratio of dense-to-buoyant subclass, to predict LDL
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BACKGROUND Recent clinical studies showed that lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) is a predictor for incident atherosclerotic disease. We have previously shown that among the LDL subfractions, Lp-PLA(2) activity is preferentially associated with the atherogenic small, dense (sdLDL) particles in vitro. We investigated whether Lp-PLA(2) could be a marker of sdLDL in human plasm...
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ژورنال
عنوان ژورنال: Obesity
سال: 2011
ISSN: 1930-7381
DOI: 10.1038/oby.2010.142